Protein Purification
Abcam NCH 51, HDAC inhibitor, 10MG
MW 390.6 Da, Purity >99%. Novel HDAC inhibitor (IC₅₀ values are 32, 48 and 41 nM at HDAC4, HDAC1 and HDAC6, respectively). Induces apoptosis and inhibits cell growth of various malignant cells and tumor cells lines (EC₅₀ = 3.8 μM). Also reactivates latent HIV-1 gene expression.
The product is subject to the following: Abcam Restricted Use Statement
Genscript Corporation MSLN/Mesothelin298-600 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF)
Abcam Compound 401, DNA-dependent protein kinase and mTOR inhibitor, 50MG
MW 281.31 Da, Purity >99%. Selective, reversible DNA-dependent protein kinase and mTOR inhibitor (IC₅₀ values are 0.28 and 5.3 μM respectively). No affinity for PI3K, ATM and ATR (IC₅₀ values are >100 μM). Able to induce apoptosis in vitro. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Hampton Research HR2-932-A1/Grid Screen Sodium Chloride #A1/Grid Screen Salt HT (G01), 185 ml - 0.1 M Citric acid pH 4.0, 1.0 M Sodium chloride
HR2-932-A1/Grid Screen Sodium Chloride #A1/Grid Screen Salt HT (G01), 185 ml - 0.1 M Citric acid pH 4.0, 1.0 M Sodium chloride. Please note items from this supplier are non-returnable.
AdipoGen NUCB2 mouse rec His
Protein. Mouse nucleobindin-2 aa 25-420 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Purity >90% SDS-PAGE. Nucleobindin-2 NUCB2 Prepronesfatin was first isolated in adipocytes, but is also expressed by gastric mucosa and pancreatic beta cells. This pattern of nucleobindin-2 expression, as well as the presence of nucleobindin-2 within the plasma of rodents and humans, strongly suggests that this compound may act as a circulating regulatory factor. NUCB2 can be cleaved into three polypeptides nesfatin-1, nesfatin-2, and nesfatin-3. Anorexigenic effects have been described for nesfatin-1 that plays an important role in hypothalamic pathways regulating food intake and energy homeostasis and acting in a leptin-independent manner. Nesfatin-1 may also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
ABclonal Technology PARP1 Rabbit pAb
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Genscript Corporation Monofinity A Resin Prepacked C
GenScript s Monofinity A Resin is made of recombinant protein A as ligand which not only keeps the specific binding capacity to Fc region of immunoglobulin molecules but also enhances chemical stability under Cleaning-in-place (CIP) conditions Monofinity A Resin Prepacked Column 1mlx1
LUNA NANOTECH INC Maxi Silica Spin Columns, 10 Columns
PuroSPIN™ MAXI Spin Columns for DNA / RNA Extraction and Purification, 10 columns
Have you ever ran out of columns that come with your favorite plasmid extraction kit but still had a lot of left-over buffer reagents remaining? Instead of buying a new expensive kit you can use PuroSPIN™ columns with the left-over buffers as a cost-effective alternative. Simply use PuroSPIN™ columns while following the manufacturer-specific protocols.
Nucleic acid binding capacity: 2.3 mg of genomic DNA, 500 µg of plasmid DNA
Compatible as cost-effective replacement columns for Plasmid DNA purification kits from Qiagen, ThermoFisher, Bio-Rad, Promega and other manufacturers
PuroSPIN™ MAXI silica spin columns are designed for fast, simple and efficient extraction of Plasmid DNA from bacterial cultures
Cayman Chemical PKC InhIbItr 5mg
A PKCβ Inhibitor (IC50s = 21 and 5 nM, respectively); selective for PKCβ1 and PKCβ2 over PKCα, PKCε, and PKCγ (IC50s = 331, 2,807, and >1,000 nM, respectively), as well as JAK1, JAK2, and TYK2 (IC50s = 770, 3,850, and 2,310 nM, respectively); inhibits JAK3 (IC50 = 17 nM); induces apoptosis and inhibits cell cycle progression in 2F7 AIDS-related Burkitt's lymphoma cells at 14 µM